Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program

by: Iola Bonggay

The Food and Drug Administration, otherwise referred to as FDA, is a federal government agency operating within the United States Department of Health and Human Services that is primarily responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs.

The grants and programs of the FDA are all geared towards the achievement of its primary agency mission which is to "protect consumers and enhance public health by maximizing compliance of FDA regulated products and minimizing risk associated with those products."

In this capacity, the Food and Drug Administration has recently established the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program in an attempt to study the effects of various physicochemical properties of ophthalmic suspensions and emulsions on ocular bioavailability.

To this effect, the program will cover the key physicochemical properties which may impact clearance, distribution, and drug release; specifically globule/particle size distribution, surface change, osmolality, pH, viscosity, and dispersibility.

It is known that there are several kinds of opthalmic drugs which are available in the market today. The goal of this study is to determine which manufacturing differences may result in physicochemical differences which in turn may affect clearance, distribution, and release of the drug.

  (continued...)

Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
  Page 2

About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

National Science Foundation's Smart Health and Wellbeing Program
The National Science Foundation has constituted the development of the Smart Health and Wellbeing (SHB) Program wherein they intend to address scientific and technical issues that would pave the way towards the transformation of the healthcare process from being rather reactive and hospital centered into becoming preventive, proactive, evidence-based, patient-centered and focused on the wellbeing of the person rather than his/her disease.

---

Health Care Fraud Program Expansion and Senior Medical Patrol Capacity Building Grants
In line with this mission, the Administration on Aging has recently established the Health Care Fraud Program Expansion and Senior Medical Patrol Capacity Building Grants in an attempt to boost the capacity of the Senior Medicare Patrol (SMP) program to reach more Medicare and Medicaid beneficiaries, their families and caregivers, while focusing on fraud prevention and identification.

---

Cancer Education Grants Program
The National Cancer Institute has developed the Cancer Education Grants Program wherein it seeks to financially support innovative educational efforts that would contribute to the reduction of cancer incidences, morbidity and mortality rates; as well as the improvement of the quality of life of surviving cancer patients.

---

Capacity Building Assistance to Improve Health in Tribal Populations Program
In keeping with all its existing programs and objectives, the Centers for Disease Control and Prevention has recently established a funding opportunity to promote the Capacity Building Assistance to Improve Health in Tribal Populations Program.

---