Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program

by: Iola Bonggay

The Food and Drug Administration, otherwise referred to as FDA, is a federal government agency operating within the United States Department of Health and Human Services that is primarily responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs.

The grants and programs of the FDA are all geared towards the achievement of its primary agency mission which is to "protect consumers and enhance public health by maximizing compliance of FDA regulated products and minimizing risk associated with those products."

In this capacity, the Food and Drug Administration has recently established the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program in an attempt to study the effects of various physicochemical properties of ophthalmic suspensions and emulsions on ocular bioavailability.

To this effect, the program will cover the key physicochemical properties which may impact clearance, distribution, and drug release; specifically globule/particle size distribution, surface change, osmolality, pH, viscosity, and dispersibility.

It is known that there are several kinds of opthalmic drugs which are available in the market today. The goal of this study is to determine which manufacturing differences may result in physicochemical differences which in turn may affect clearance, distribution, and release of the drug.

  (continued...)

Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
  Page 2

About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Rheumatic Diseases Research Core Centers Project
The National Institutes of Health, in close cooperation with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), has established a program entitled Rheumatic Diseases Research Core Centers Project wherein they intend to solicit applications for the development of Research Core Centers concentrating on rheumatic diseases.

---

Shared Instrumentation Grant Program
The National Institutes of Health has recently established the Shared Instrumentation Grant Program wherein they intend to solicit applications from NIH-supported research proposing to upgrade or purchase a single piece of expensive instrumentation (useful to the field of science and technology) that at a minimum costs $100,000.

---

Cancer Research Network: a Research Resource within Health Care Delivery System
In cooperation with the National Cancer Institute, the National Institute of Health has recently announced a funding opportunity to support the Cancer Research Network(CRN) in its quest in reshaping the its organization to become a more broader resource for cancer researchers.

---

Health Care Fraud Program Expansion and Senior Medical Patrol Capacity Building Grants
In line with this mission, the Administration on Aging has recently established the Health Care Fraud Program Expansion and Senior Medical Patrol Capacity Building Grants in an attempt to boost the capacity of the Senior Medicare Patrol (SMP) program to reach more Medicare and Medicaid beneficiaries, their families and caregivers, while focusing on fraud prevention and identification.

---