Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
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b) Basic research that will determine the mechanisms involved in temporal establishment, maintenance, and resurgence of CNS-based HIV-1 reservoirs in relation to the effects and timing of HAART, viral expression, and viral evolution within the patient's brain.

c) The creation of several physiologically relevant animal models and CNS-based cellular assays that recapitulate HIV-1 persistence and latency in the presence of efficient HAART management.

d) Drug screening of potential agents that go beyond the blood-brain barrier and eliminate latent or other sources of residual virus within the CNS.

e) Design of therapeutic strategies aimed towards the eradication of HIV-1 from the CNS.

The funding agencies are set to administer funds in the amount of $2 million to support the initiatives of the program.

The institutions and organizations who will be considered eligible to submit an application under this program are the following:

a) Higher Education Institutions

b) Hispanic-serving Institutions and Historically Black Colleges and Universities (HBCUs)

c) Nonprofit organizations other than institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, and Special District Governments

f) Independent School Districts

g) Public Housing Authorities

h) Faith-based or Community-based Organizations, and Regional Organizations.

Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
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About The Author Michael Saunders is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. He also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Basic Research on HIV Persistence Program
In keeping with this mission, the National Institutes of Health has recently constituted the establishment of the Basic Research on HIV Persistence Program in an attempt to increase our understanding of the persistence of HIV-1 infections in patients under highly active anti-retroviral therapy (HAART).

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National Institutes of Health funds the Improving Adherence to Treatment Regimens for HIV-Positive Adolescents and Young Adults
The National Institutes of Health has recently established a program entitled Improving Adherence to Treatment Regimens for HIV-Positive Adolescents and Young Adults wherein they intend to kick-off research studies that will create, implement, and evaluate both old and new interventions that are geared towards improving adherence to medical and behavioral regimens for HIV-positive adolescents which are 11 to 21 years old and adults who are 21 to 24 years old.

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Identifying Heart, Lung, and Blood Disease-Causing Variants
The National Institutes of Health has formed a partnership with the National Heart, Lung, and Blood Institute to establish a program that aims to Identify Heart, Lung, and Blood Disease-Causing Variants.

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Mechanisms Mediating Osteoarthritis in Aging
The National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

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