Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
Page 2

b) Basic research that will determine the mechanisms involved in temporal establishment, maintenance, and resurgence of CNS-based HIV-1 reservoirs in relation to the effects and timing of HAART, viral expression, and viral evolution within the patient's brain.

c) The creation of several physiologically relevant animal models and CNS-based cellular assays that recapitulate HIV-1 persistence and latency in the presence of efficient HAART management.

d) Drug screening of potential agents that go beyond the blood-brain barrier and eliminate latent or other sources of residual virus within the CNS.

e) Design of therapeutic strategies aimed towards the eradication of HIV-1 from the CNS.

The funding agencies are set to administer funds in the amount of $2 million to support the initiatives of the program.

The institutions and organizations who will be considered eligible to submit an application under this program are the following:

a) Higher Education Institutions

b) Hispanic-serving Institutions and Historically Black Colleges and Universities (HBCUs)

c) Nonprofit organizations other than institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, and Special District Governments

f) Independent School Districts

g) Public Housing Authorities

h) Faith-based or Community-based Organizations, and Regional Organizations.

Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
  Back to Page 1

About The Author Michael Saunders is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. He also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Basic Research on HIV Persistence Program
In keeping with this mission, the National Institutes of Health has recently constituted the establishment of the Basic Research on HIV Persistence Program in an attempt to increase our understanding of the persistence of HIV-1 infections in patients under highly active anti-retroviral therapy (HAART).

---

Children Youth and Families At-Risk Sustainable Community Project
The The National Institute of Food and Agriculture, in close cooperation with the United States Department of Agriculture, has established a funding opportunity to support the Children Youth and Families At-Risk Sustainable Community Project (CYFAR).

---

Pilot Studies of Innovative Treatments in Mental Disorders Project
The National Institutes of Health has recently collaborated with the National Institutes of Mental Health (NIMH) to establish the Pilot Studies of Innovative Treatments in Mental Disorders Program.

---

Development of Therapeutics and Diagnostics for Biodefense Program
The National Institutes of Health, in partnership with the National Institute of Allergy and Infectious Diseases(NIAID), has established the Development of Therapeutics and Diagnostics for Biodefense Program in an attempt to seek research proposals that desire to support the development of lead candidate diagnostics or therapeutics against NIAID Category A, B, or C priority agents.

---