Mechanisms Mediating Osteoarthritis in Aging

by: TopGovernmentGrants Editorial Staff

The National Institutes of Health, otherwise known as NIH, is an agency operating within the United States Department of Health and Human Services that is primarily responsible for pursuing all of the country's biomedical and health-related research studies.

The actions of the NIH are carefully guided by their overall agency mission which is to obtain a deeper understanding of medical conditions that could potentially help them detect, prevent, diagnose, and treat diseases and disabilities.

In line with this objective, the National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

Osteoarthritis is a common degenerative joint disease that usually affects the elderly population from 50 to 80 years old and above. The disease limits the mobility of the person and brings so much pain and inconvenience. It is often associated with mechanical abnormalities involving degradation of joints including articular cartilage and subchondral bone. The symptoms of this degenerative disease condition are joint pain, tenderness, stiffness, locking, and joint effusion.

The program aims to obtain a deeper understanding of the mechanisms that are involved in osteoarthritis through conducting research studies on genetically defined and modified mouse models, dogs, monkeys, and even archived human joints.

  (continued...)

Mechanisms Mediating Osteoarthritis in Aging
  Page 2

About The Author The TopGovernmentGrants Editorial Staff maintains one the most comprehensive Websites offering information on government grants and federal government programs. The staff also provides resources to other Websites with information on grants for youth programs and home improvement grants.

Additional Resources

category - Health Grants

Critical Congenital Heart Disease Newborn Screening Demonstration Program
The Health Resources and Services Administration has recently constituted the Critical Congenital Heart Disease (CCHD) Newborn Screening Demonstration Program in order to support and encourage the development, dissemination, and validation of screening protocols and newborn screening infrastructure for point of care screenings that are specific to Critical Congenital Heart Diseases.

---

Department of Human Health and Services: Family Planning Services Grant
OPHS has recently announced the availability of funding opportunities for the establishment and implementation of voluntary family planning service projects.

---

HRSA: Reducing Loss to Follow-up after Failure to Pass Newborn Hearing Screening
Reducing to Loss of Follow-up after Failure to Pass Newborn Hearing Screening program enables eligible health care institutions to solicit funds by establishing project proposals that would greatly improve the number of infants receiving appropriate and timely follow-ups through the utilization of patient-centered interventions.

---

Exploratory Clinical Trials for Small Business Grant Program
The National Institutes of Health has formed a partnership with the National Institute of Neurological Disorders and Stroke (NINDS) in order to establish the Exploratory Clinical Trials for Small Business Grant Program wherein they aim to establish a vehicle for Small Business Concerns (SBCs) in the process of submitting Small Business Technology Transfer (STTR) grant applications for exploratory clinical trials directly to the NIND

---