Mechanisms Mediating Osteoarthritis in Aging

by: TopGovernmentGrants Editorial Staff

The National Institutes of Health, otherwise known as NIH, is an agency operating within the United States Department of Health and Human Services that is primarily responsible for pursuing all of the country's biomedical and health-related research studies.

The actions of the NIH are carefully guided by their overall agency mission which is to obtain a deeper understanding of medical conditions that could potentially help them detect, prevent, diagnose, and treat diseases and disabilities.

In line with this objective, the National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

Osteoarthritis is a common degenerative joint disease that usually affects the elderly population from 50 to 80 years old and above. The disease limits the mobility of the person and brings so much pain and inconvenience. It is often associated with mechanical abnormalities involving degradation of joints including articular cartilage and subchondral bone. The symptoms of this degenerative disease condition are joint pain, tenderness, stiffness, locking, and joint effusion.

The program aims to obtain a deeper understanding of the mechanisms that are involved in osteoarthritis through conducting research studies on genetically defined and modified mouse models, dogs, monkeys, and even archived human joints.

  (continued...)

Mechanisms Mediating Osteoarthritis in Aging
  Page 2

About The Author The TopGovernmentGrants Editorial Staff maintains one the most comprehensive Websites offering information on government grants and federal government programs. The staff also provides resources to other Websites with information on grants for youth programs and home improvement grants.

Additional Resources

category - Health Grants

Rheumatic Diseases Research Core Centers Project
The National Institutes of Health, in close cooperation with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), has established a program entitled Rheumatic Diseases Research Core Centers Project wherein they intend to solicit applications for the development of Research Core Centers concentrating on rheumatic diseases.

---

Rural Health Research Center Program
The Health Resources and Services Administration has recently established the Rural Health Research Center (RHRC) Cooperative Agreement Program in an attempt to substantially improve the amount of high-quality, impartial, policy-relevant research studies.

---

Small Business Innovation Research Phase IIB Bridge Awards
In line with this mission, the NIH has recently constituted the Small Business Innovation Research Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics Toward Commercialization Program.

---

Identifying Heart, Lung, and Blood Disease-Causing Variants
The National Institutes of Health has formed a partnership with the National Heart, Lung, and Blood Institute to establish a program that aims to Identify Heart, Lung, and Blood Disease-Causing Variants.

---