Mechanisms Mediating Osteoarthritis in Aging

by: TopGovernmentGrants Editorial Staff

The National Institutes of Health, otherwise known as NIH, is an agency operating within the United States Department of Health and Human Services that is primarily responsible for pursuing all of the country's biomedical and health-related research studies.

The actions of the NIH are carefully guided by their overall agency mission which is to obtain a deeper understanding of medical conditions that could potentially help them detect, prevent, diagnose, and treat diseases and disabilities.

In line with this objective, the National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

Osteoarthritis is a common degenerative joint disease that usually affects the elderly population from 50 to 80 years old and above. The disease limits the mobility of the person and brings so much pain and inconvenience. It is often associated with mechanical abnormalities involving degradation of joints including articular cartilage and subchondral bone. The symptoms of this degenerative disease condition are joint pain, tenderness, stiffness, locking, and joint effusion.

The program aims to obtain a deeper understanding of the mechanisms that are involved in osteoarthritis through conducting research studies on genetically defined and modified mouse models, dogs, monkeys, and even archived human joints.

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Mechanisms Mediating Osteoarthritis in Aging
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Additional Resources

category - Health Grants

Excellence in Hemoglobinopathies Research Award Program
The National Institutes of Health has formed a collaboration with the National Heart, Lung, and Blood Institute (NHLBI) in an effort to establish the Excellence in Hemoglobinopathies Research Award Program wherein both agencies have agreed to financially support the creation of studies that could potentially improve high-impact multi-disciplinary basic and translational research studies in the hemoglobinopathies.

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Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities
The National Institutes of Health has recently formed a partnership with the National Cancer Institute (NCI) in an effort to constitute the Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities wherein both agencies intend to solicit grant application from various eligible researchers who are interested in conducing basic research studies regarding the biological causes and mechanisms of cancer health disparities.

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Child Health Research Career Development Award Program
In accordance with this mission, the National Institute of Health has collaborated with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in an attempt to establish the Child Health Research Career Development Award Program.

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Environmental Exposures and Health: Exploration of Non-Traditional Settings Program
In according with this mission, the National Institutes of Health has partnered with the National Institute of Nursing Research (NINR) and the National Institute of Environmental Health Sciences (NIEHS) to establish the Environmental Exposures and Health: Exploration of Non-Traditional Settings Program.

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