Mechanisms Mediating Osteoarthritis in Aging

by: TopGovernmentGrants Editorial Staff

The National Institutes of Health, otherwise known as NIH, is an agency operating within the United States Department of Health and Human Services that is primarily responsible for pursuing all of the country's biomedical and health-related research studies.

The actions of the NIH are carefully guided by their overall agency mission which is to obtain a deeper understanding of medical conditions that could potentially help them detect, prevent, diagnose, and treat diseases and disabilities.

In line with this objective, the National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

Osteoarthritis is a common degenerative joint disease that usually affects the elderly population from 50 to 80 years old and above. The disease limits the mobility of the person and brings so much pain and inconvenience. It is often associated with mechanical abnormalities involving degradation of joints including articular cartilage and subchondral bone. The symptoms of this degenerative disease condition are joint pain, tenderness, stiffness, locking, and joint effusion.

The program aims to obtain a deeper understanding of the mechanisms that are involved in osteoarthritis through conducting research studies on genetically defined and modified mouse models, dogs, monkeys, and even archived human joints.

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Mechanisms Mediating Osteoarthritis in Aging
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Additional Resources

category - Health Grants

Lifespan Respite Care Program - Technical Assistance Resource Center
In keeping with this mission, the Administration on Aging has recently announced the constitution of the Lifespan Respite Care Program - Technical Assistance Resource Center wherein it aims to invite applications for a competitive grant opportunity for implementing the requirements of the Technical Assistance Resource Center (TARC) as authorized in the Lifespan Respite Care Act of 2006.

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Family Planning Services Grants
OPHS has recently established a funding opportunity entitled Family Planning Services Grants, a program wherein the OPHS, along with the HHS, will award grants to eligible individuals who seek to operate voluntary family planning services projects that would provide family planning services to everyone who desires to avail of such services, including low-income families in under-served areas.

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Basic Research on HIV Persistence Program
In keeping with this mission, the National Institutes of Health has recently constituted the establishment of the Basic Research on HIV Persistence Program in an attempt to increase our understanding of the persistence of HIV-1 infections in patients under highly active anti-retroviral therapy (HAART).

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Nutrition Obesity Research Centers Grant Program
In an attempt to support this mission, the National Institutes of Health has formed a partnership with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to establish the Nutrition Obesity Research Centers Grant Program wherein both agencies intend to solicit grant applications that wish to establish core centers which will be an essential part of an integrated program of nutrition and obesity research.

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