Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.

by: Iola Bonggay

The United States Food and Drug Administration, otherwise referred to as the USFDA, an agency operating within the United States Department of Health and Human Services that is generally responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs, vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices, veterinary products, and cosmetics.

The USFA has recently formed a collaboration with the National Institutes of Health to establish the Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.

The primary goal of the program is to develop computational fluid dynamics (CFD) model of orally inhaled drug products that can account for drug product characteristics and physiological parameters on total and regional deposition in the lungs.

This is all in conjunction with the USFDA's objective of developing a CFD model that will be capable of of predicting highly localized deposition of pharmaceutically relevant polydisperse aerosols from metered dose inhalers (MDIs) and dry powder inhalers (DPIs).

In addition, the results that will be derived from this study will then be utilized to create a linked CFD-compartment model that can predict the effects of lung deposition on safety (systemic exposure) and efficacy (local delivery) for locally acting orally inhaled drugs.

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Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.
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About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Medical Tropical Research Laboratory Program Infectious Disease Research Award
AFRIMS has recently announced the WRAIR Medical Tropical Research Laboratory Program(MTRLP) Infectious Disease Research Award(IDRA), a funding opportunity which solicits proposals that aim to tackle basic, preclinical and clinical research of emerging infectious diseases in Thailand and a certain region in Southeast Asia.

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The National Institutes of Health, in cooperation with the National Human Genome Research Institute, has established a funding opportunity to support the Expanding the Encyclopedia of DNA Elements in Human and Model Organisms project.

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Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care Program
The National Institutes of Health has recently established the Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care Program wherein it intends to utilize common conceptual models in creating independent interventions that will contribute to the modification of health behaviors and the improvement of health outcomes in patients diagnosed with co-morbid chronic diseases and health conditions.

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Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.
The USFA has recently formed a collaboration with the National Institutes of Health to establish the Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.

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